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Slavery was the major cause of the American Civil War, with the South seceding to form a new country to protect slavery, and the North refusing to allow that. Historians generally agree that other economic conflicts were not a major cause of the war.
The Second Civil War
The Stage is set
In yet another expression of lame-duck pique, President Donald Trump has threatened to veto the 2021 National Defense Authorization Act over provisions to rename military bases that honor Confederate generals. Trump is apparently calculating that lawmakers will capitulate rather than risk holding up $740 billion in funding for the military. Senate Republicans should prove him wrong.
https://www.history.com/topics/american-civil-war/american-civil-war-history